at this resolution would have limited ability to detect changes in cortical thickness, and may even result in different volumes of brain compartments due to partial volume effects at borders between tissue types. More subtle confounds can arise from image distortions specific to each individual MRI scanner, which can result in measurement differences despite otherwise similar image parameters (Jovicich et al., 2006). A strength of the NIMH investigation has been the stability of the MRI platform and acquisition parameters throughout the duration of the study.
