For adult AAD symptoms sum score, data were drawn from wave 2. All sum AAD counts were assessed using DSM IV criteria. Only phenotypic data for subjects who had previously used alcohol were included. Of the 246 adult subjects with no dependence symptoms, 25.6% of them endorsed an abuse criterion. Sum symptom counts were standardized using the CADD community sample as above for CD and adolescent AAD. For the analysis only subjects assessed at wave 2 that were also included in the adolescent/young adult analyses of CD and AAD were analyzed. The analysis was performed on 703 subjects.