For the adolescent/young adult AAD symptoms sum score, data were drawn from wave 1 of data collection. All sum AAD counts were assessed using DSM IV criteria. Only phenotypic data for subjects who had previously used alcohol were included; in other words, if a subject had never had a drink of alcohol they were excluded from the analysis. Of the 492 adolescent subjects with no dependence symptoms, 25.6% of them endorsed an abuse criterion, strengthening the argument for inclusion of abuse symptoms. Sum symptom counts were standardized in the same manner described for CD above, using residuals and coefficients derived in the community sample and applying these to the clinical subjects. After standardization, only phenotypic data from subjects between the ages of 10 and 25 were included for analysis. The analysis was performed on 1,199 subjects.
