We used the Panther Database41 to obtain details of the gene molecular function and biological process. Genes are grouped into 28 top-level molecular function groups and 30 top-level biological process groups, with each gene allowed to exist in more than one group. We identified 14,979 non-overlapping autosomal genes from the Panther RefSeq Annotation for which we could obtain recombination rates. Of these, 9,735 had at least one assigned molecular function and 9,432 had at least one assigned biological process. Genes without a molecular function or biological process were removed from the corresponding analysis. To control for gene size, we estimated the mean recombination rate over a 20-kb region centred on the mid-point of each gene transcription region.
