Meta-analysis summary statistics were uploaded to FUMA, which identified 35 lead SNPs based on p-value and linkage disequilibrium; these are presented in Table 2 alongside functional information derived from Combined Annotation Dependent Depletion (CADD (Kircher et al., 2014)) scores and RegulomeDB (Boyle et al., 2012). Overall, these markers are not predicted to be especially deleterious – only one marker has a CADD score >10 – nor are they predicted to have meaningful regulatory roles – no marker has a RegulomeDB score of 1a-1f.
