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Chunk #27 — FUTURE DIRECTIONS

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Enrichr: a comprehensive gene set enrichment analysis web server 2016 update.
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As more genomics, transcriptomics and proteomics data accumulate, we plan to continue adding to Enrichr new gene set libraries. We also plan to continually improve the visualization of the enrichment results. It might be useful for users to view results across libraries, and to have a report of the most interesting enrichment results across all libraries. Enrichr currently supports only input from mammalian genes; in the future, we plan to add versions of Enrichr for yeast, worm and fly. The collection of terms for genes can be used to identify similarity between genes across resources, and this will improve the Find a Gene feature by suggesting similar genes. By examining the lists submitted to Enrichr, we noticed that approximately 10% of the submitted lists do not contain valid gene names. Users submit probe IDs, protein IDs, genes from other organisms, complete tables from spreadsheets with special characters, and other non-standard genes names. To accommodate these users, Enrichr needs to provide methods to convert these inputs into usable gene sets. The enrichment analysis concept can be expanded into new directions. For