0.05). Figures 3 and 4 depict comparisons of power between EEE approximated power versus simulated power values for these two scenarios. A total of 208 data-points from 5 published studies [3, 5, 11, 18, 20] are included in Figures 3 and 4. The CCC between simulated study power and EEE power was 0.9802 (95% CI 0.974 – 0.9849) corresponding to Figure 3 and 0.9840 (95% CI 0.9791 – 0.9877) corresponding to Figure 4, respectively. The Pearson correlation coefficients were 0.9803 and 0.9499. The descriptive statistics for PPD and APPD are given in Tables 3 and 4 corresponding to Figures 3 and 4, respectively. There were only 4 observations in Figure 3 and 5 observations in Figure 4 for which the difference between the EEE approximated and simulated power was more than 10%, again showing extreme concordance with the power calculated by EEE and simulated study power. Note that Lin’s CCC and Pearson correlation coefficients are quite similar in all scenarios presented here.
