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Chunk #18 — RESULTS

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Externalizing disorders in American Indians: comorbidity and a genome wide linkage analysis.
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Comorbidity of each disorder was evaluated by comparing the frequencies of that disorder in the alcohol dependent and non-alcohol dependent groups of individuals. As shown in Table 3, odds ratios and 95% confidence intervals were calculated for each externalizing disorder group for the entire group and men and women separately. Alcohol dependence was found in 65% of the men and 54% of the women in the total sample. Alcohol dependence was found to be comorbid with: ASPD (p<0.001) ASPD/CD (p<0.001) but did not reach significance for CD alone (p<0.1). Alcohol dependence was also found to be comorbid with ASPD, and ASPD/CD in men and women when they were analyzed separately. However, CD was not found to be significantly comorbid with alcohol dependence in either men or women. Similar results were found in the linkage sample.