Chunk #13 — 3.0 Summary of Small-Sample Covariance Estimators

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Modification of the Sandwich Estimator in Generalized Estimating Equations with Correlated Binary Outcomes in Rare Event and Small Sample Settings.

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The problems caused by rare outcomes relative to the use of GEE models were first noted by Gunsolley while exploring the performance of GEEs with binary outcomes using a compound symmetry covariance structure [7].