Chunk #34 — Results — Organoids derived from schizophrenia iPSCs—dispersion of proliferating cells in the cortex and blockade of cortical neuronal development

Source

Cerebral organoids reveal early cortical maldevelopment in schizophrenia-computational anatomy and genomics, role of FGFR1.

Embedded

yes

Text

Together, our observations showed proliferation and migration of the schizophrenia NPCs, premature development of neurons in the subcortical region, and impaired neuronal development in the forming cortex of the schizophrenia organoids.