Study limitations are noted. Only common psychiatric disorders were assessed. Some population segments were not included, e.g., prisoners, homeless, long-term inpatients. NESARC-III was also cross-sectional. Prospective surveys are needed to investigate the stability and causal directions of the relationships. The study also did not distinguish between associations explained by greater use of cannabis or greater risk of a disorder given such use; future studies should address this issue. NESARC-III also had important strengths, including a large sample, reliable and valid measures, and rigorous field methodology. NESARC-III is also unique in providing current, comprehensive information on DSM-5 cannabis use disorder and its correlates and comorbidity in the U.S. adult general population.
