Chunk #24 — The search for gene variants related to alcohol sensitivity (See Table 1) — GABA-related genes

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A Critical Review of Methods and Results in the Search for Genetic Contributors to Alcohol Sensitivity.

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GABRG1 (chromosome 4p12) variants in rs1391166 and rs1497571 are potentially related to low SRE-based alcohol sensitivity. Subjects with rs1497571 CC genotype had lower LRs per drink, higher drinks per occasion, and more alcohol problems (Ray and Hutchison, 2009).