For the three pairs of adjacent contacts we then extracted from the temporally averaged synchronization matrices of each patient the mean degree of synchrony within the entorhinal cortex, between entorhinal cortex and hippocampus, and within the hippocampus, respectively (Figure 2A), and compared these mean values across patients using a nonparametric test (two-sided Wilcoxon signed-rank test). This procedure ensured that the compared synchrony values were calculated from pairs of contacts that were all spaced at the same distance.
