Chunk #13 — Results — LDL Cholesterol

Source

Association of blood lipids with common DNA sequence variants at 19 genetic loci in the multiethnic United States National Health and Nutrition Examination Survey III.

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SNPs at three loci (TRIB1, LDLR, and CILP2/PBX4) were significantly associated with LDL cholesterol in at least one non-white ethnic group. TRIB1 rs17321515 and LDLR rs1529729 were significantly associated with LDL cholesterol (P = 0.0004 and P = 0.02, respectively) in Mexican Americans. CILP2/PBX4 rs3794991 and LDLR rs6511720 were associated with LDL cholesterol in non-Hispanic blacks (P = 0.04 and P = 8.6 × 10−5, respectively).