Chunk #12 — Results — LDL Cholesterol

Source

Association of blood lipids with common DNA sequence variants at 19 genetic loci in the multiethnic United States National Health and Nutrition Examination Survey III.

Embedded

yes

Text

In addition to 1p13, HMGCR rs12654264 was associated with LDL cholesterol in non-Hispanic blacks (P = 0.006), Mexican Americans (P = 0.01), and non-Hispanic whites (P = 0.05). As in the original discovery studies, the minor T allele was associated with higher LDL cholesterol in each of the ethnic groups from NHANES III.2, 18