In collaboration with the Gene Expression Database (GXD), we deployed a new interface that allow users to compare gene expression and phenotype data for a given gene (see also Smith CM et al., 12). The new Phenotype/Gene Expression Comparison Matrix, accessible from the Expression and Mutations, Alleles and Phenotype section of MGD’s gene detail pages, visually juxtaposes information about tissues where a gene is normally expressed against tissues where mutations in that gene cause abnormal phenotypes (Figure 2). Using this new data display tool researchers may explore the molecular mechanisms of disease by answering such questions as ‘What tissues affected by a gene mutation also show expression of that gene?’ or ‘What tissues affected by a gene mutation do not express that gene?’.
