identified genes differentially expressed between the ethanol drinking and control animals (Supplementary Table 1). Key functional groups of genes that were altered in expression included neurotransmitter systems (Table 1), neuropeptide systems (Table 2), ion channels (Table 3), and genes related to cAMP, CREB, inflammation, oxidative stress, axonal guidance as well as many growth factors and transcription factors (Table 4, Supplementary Table 2). Pathways identified from genes overlapping with human studies (Supplementary Table 5) highlight pathways related to oxidative stress, inflammation, cAMP, CREB, axonal guidance, dopamine and serotonin.
