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Chunk #2 — 1. Introduction

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A Prospective Comparison of Bipolar I and II Subjects with and without Comorbid Cannabis Use Disorders from the COGA Dataset.
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A recent review indicates that lifetime cannabis use (CU) was very frequent among persons with BD, ranging from 50–66% using cannabis over their lifetime [8]. This reported rate of lifetime cannabis use (LT-CU) is as much as sevenfold higher in individuals with BD compared to people without BD (71.3%, OR 6.8, CI, 5.41 to 8.52) [9], while cross-sectional prevalence rates of CU varied from 3.3% to approximately 18% [8].