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Chunk #17 — Materials and methods — Statistical analysis

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Catechol-o-methyl transferase (COMT) val158met polymorphism and adolescent cortical development in patients with childhood-onset schizophrenia, their non-psychotic siblings, and healthy controls.
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This model was run once for each possible contrast between the three clinical groups: HC, COS probands and SIBs. Regions where the t-statistic associated with the β8 coefficient (differences between two clinical groups in the rate of CT change with increasing Val dose) was significant after False Discovery Rate correction for multiple comparisons (q = 0.05) were visualized by projection onto a standard cortical surface.