Chunk #16 — Materials and methods — Statistical analysis

Source

Catechol-o-methyl transferase (COMT) val158met polymorphism and adolescent cortical development in patients with childhood-onset schizophrenia, their non-psychotic siblings, and healthy controls.

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Then, to contrast the relationship between Val158Met genotype and cortical development between different participant groups, CT for ith family's jth individual's kth time-point was modeled as: CTijk=Intercept+di+dij+β1(sex)+β2(mean age)+β3(Val dose)+β4(Clinical Group)+β5(mean age*Val dose)+β6(mean age*Clinical Group)+β7(Val dose*Clinical Group)+β8(mean age*Val dose*Clinical Group)+eijk