deletion of 13q14 was observed in 5 leukemia cases, but also in 18 individuals with solid tumors (9 with lung cancer and 4 with prostate cancer), and in 10 cancer-free individuals. This region includes the tumor suppressor gene DLEU7 (Deleted In Leukemia 7) and related genes, DLEU1 and DLEU2, the latter harboring two microRNAs within one of its introns (miR-15a and miR-16-1)24-26. The retinoblastoma gene, RB1 was also included within a subset harboring a mosaic deletion of 13q14. It cannot be ruled out that these individuals have either undiagnosed CLL or MBL. The 20q- was seen in two individuals with myeloid leukemia as has been described previously27 but also in cancer-free and individuals with solid tumors.
