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Chunk #23 — Results — Cis-associations of gene expression with SNPs

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Complex nature of SNP genotype effects on gene expression in primary human leucocytes.
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An identical analysis was performed on publicly available EBV-transformed B cell line expression and genotype data for 90 CEU HapMap individuals [3]. Using this dataset and a SNP-probe distance of 500 kb and FDR of 0.01 or 0.05, 1,799 and 2,839 different SNP-probe effects were detected, respectively. These reflect 536 and 821 unique probes, and 1,601 and 2,464 unique SNPs, respectively (see Table 1). Details of all detected individual cis-eQTLs are available in Additional file 1.