Chunk #27 — Methods — Stereotaxic injections — 6-OHDA unilateral injection and behavioral assessment

Source

Striatal Neurons Expressing D and D Receptors are Morphologically Distinct and Differently Affected by Dopamine Denervation in Mice.

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Thirty days after surgery, mice from the two experimental groups were introduced in a large glass cylinder and spontaneous motor behavior was recorded during 10 min. Spontaneous rotations were counted by a blinded experimenter. Complete ipsilateral and contralateral rotations to the 6-OHDA-lesioned side were counted and used as behavioral indication of the severity of the DA lesion.