We define the following composite statistics: permuted Z density statistics: Zdensity(q)=medianα∈Density statistics(Zα(q))permuted Z connectivity statistics: Zconnectivity(q)=medianα∈Connectivity statistics(Zα(q)) Lower (negative) values of z-scores indicate larger relative non-preservation of the reference module in the test network. Empirical z-scores are then converted into empirical P values using the normal cumulative distribution function.
