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Chunk #17 — DISCUSSION

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Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains.
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The present study identified 27 genome-wide significant loci in the largest GWAS of ADHD to date. We analyzed around twice as many ADHD cases compared to the ADHD201914 study and more than doubled the number of associated loci, indicating that we have passed the inflection point for ADHD with respect to the rate of risk loci discovery.