Chunk #15 — Materials and methods — Case studies of specific loci

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Integration of GWAS SNPs and tissue specific expression profiling reveal discrete eQTLs for human traits in blood and brain.

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Identical statistical models were utilized to test our ability to detect known-associated eQTLs in previously published reports in tissues not previously investigated in GWAS. Results for these loci were mined for all associations within each +/− 500 kb region around top SNPs within each locus from the published GWAS within each tissue.