Chunk #14 — Materials and methods — Expression QTL analyses

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Integration of GWAS SNPs and tissue specific expression profiling reveal discrete eQTLs for human traits in blood and brain.

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Significant associations were determined within each tissue type using a 5% FDR adjustment for multiple testing. Proportions of tested associations were calculated per tissue based on this subset of the eQTL results, and were compared using simple chi-squared tests.