DNA and phenotypic information were obtained anonymously from 727 subjects who participated in Project MATCH, a large, multi-center trial comparing the effects of three different psychosocial interventions. The diagnosis of AD for Project MATCH subjects was made using the Computerized Diagnostic Interview for DSM-IV (Blouin et al. 1988; American Psychiatric Association 1994). Institutional review boards at UCHC, Yale, and the Medical University of South Carolina (where Project MATCH blood samples were stored prior to DNA extraction and genotyping) approved the use of coded Project MATCH samples.
