ANOVA also revealed a dipole site by hemisphere interaction in patients with anxiety disorder, which confirmed that hemispheric asymmetry is dependent on the dipole site (F(1,94) = 24.35, P < 0.001). Specifically, the right-greater-than-left asymmetry of the P300 amplitude was more prominent in the temporal dipole compared with the frontal dipole. A dipole site by hemisphere interaction in depressive disorder patients confirmed that the left-greater-than-right asymmetry of the P300 amplitude was more prominent in the temporal dipole compared with the frontal dipole (F(1,94) = 19.15, P < 0.001). This interaction effect was not significant in the healthy control group (F(1,94) = 0.591, P = 0.430).
