ANOVA analysis also indicated a main effect of hemisphere on dipole P300 amplitude (F(1,94) = 9.57, P < 0.01). The dipole P300 amplitude was greater in the right compared with the left hemisphere in patients with anxiety disorders, indicating that the hemispheric effect was significantly right-greater-than-left asymmetry (F(1,94) = 17.70, P < 0.001). In contrast, the dipole P300 amplitude was greater in the left compared with the right hemisphere in depressive disorder patients, resulting in an hemispheric effect on dipole amplitude that had significant left-greater-than-right asymmetry (F(1,94) = 21.15, P < 0.001). In the healthy control group, the hemispheric effect was not significant (F(1,94) = 1.52, P = 0.257).
