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Chunk #28 — 3. Results — 3.3. Effects of ethanol on protein levels in W rats

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Differential effects of ethanol in the nucleus accumbens shell of alcohol-preferring (P), alcohol-non-preferring (NP) and Wistar rats: a proteomics study.
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Among the 28 proteins that were altered by ethanol in the ACB-shell of W rats (Table 5), there were 11 that were similarly changed in P or NP rats. Only one protein changed in the opposite direction with ethanol treatment in the W rats versus either P or NP rats, i.e., 19 kDa protein had lower expression levels in the ethanol-treated W rats and higher levels in the ethanol-treated NP line. Therefore, expression levels of 17 proteins were uniquely changed by ethanol in the ACB-shell of W rats (Table 5).