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Chunk #45 — Methods — SNP-based heritability and genetic correlations

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Item-level analyses reveal genetic heterogeneity in neuroticism.
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The genetic correlations between the 15 neuroticism phenotypes and 33 sundry traits for which summary statistics were available, were also calculated using LD score regression. We corrected for multiple testing through a stringent Bonferroni correction leading to a P value threshold of P < 1.01 × 10−4 (0.05/(15 × 33) = 0.05/495).