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Chunk #18 — Results — FUMA covers various features of existing tools

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Functional mapping and annotation of genetic associations with FUMA.
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Visualization is one of the essential features that allows (quick) insights into the GWAS results, e.g., summarizing annotated information of SNPs and genes. LocusZoom is one of the most widely used visualization tool for GWAS results which plots LD structure of a risk locus, gene locations as well as SNP association values40. LocusTrack is an extension of LocusZoom which also plots additional information together such as Chip-seq and chromatin state41. 3D Genome Browser is a recently developed web application which contains comprehensive 3D chromatin interaction datasets such as Hi-C and ChIA-PET42, though it does not integrate with GWAS summary statistics. These tools are primarily focused on visualization of a subset of functionally relevant data sources. FUMA integrates results from multiple lines of evidence and provides interactive visualization of results, facilitating rapid interpretation.