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Chunk #3 — INTRODUCTION

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Externalizing disorders in American Indians: comorbidity and a genome wide linkage analysis.
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pathologies including drug addictions (DeWit et al., 2000; York, 1999). An alternate hypothesis has been forwarded suggesting that drug addictions and psychopathology are in fact a reflection of a more general underlying susceptibility to disinhibitory behavior and/or behavioral under-control that may emerge at a young age and influence the initiation of substance use (Clark et al., 2005; Iacono et al., 2002; Jessor and Jessor, 1977; Mc Gue et al., 2006; Slutske et al., 1998, 2002; Wong et al., 1999).