All details related to the statistical parameters for the reported experiments are included in the figure legends. For the hPSC experiments, CRISPRi experiments, and mouse studies, the average gene expression levels or changes in lipid levels were compared between groups using the two-tailed Welch’s t-test, due to the groups having unequal sizes in some experiments. Statistical analyses regarding these functional studies were performed using GraphPad Prism 6 for Mac OS X.
