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Chunk #34 — DISCUSSION

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Genome-wide association study of bipolar disorder in European American and African American individuals.
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Different putative associations were observed among individuals of EA and individuals of AA when analyzed separately, and analyses assessing the extent to which some SNPs show genetic background-dependent effects highlighted different areas of potential association. We believe that this is the first report emerging from a GWA to explicitly address the dependency of SNP effects on ancestry, admixture, and/or genetic background.