combined with the replication datasets (p = 2.99 × 10−7 and p = 3.05 × 10−7, respectively), noting that the CPVL SNP was significant in the AA replication sample (p = 0.0024) and the effect direction was the same across all eight datasets. Two SNPs in Table 2 had significant eQTL effects in GTEx: rs11500237 on chromosome 11 near KCNA4 is a significant eQTL for ADP ribosylation factor like GTPase 14 effector protein (ARL14EP) in prostate tissue (p = 2.3 × 10−6), and rs11764430 in CVPL significantly alters the expression of two uncharacterized transcripts (p = 8.3 × 10−7, p = 3.6 × 10−6).
