In examining the relationship of psychiatric and cannabis use history to cannabis withdrawal symptoms in the subsample of frequent ‘cannabis only’ users (Table 5), age was associated with both anxiety/depression symptoms and weakness symptoms, while gender was associated with weakness symptoms only. Quantity of cannabis was significantly related to both types of withdrawal symptoms. Duration of heaviest use (less than one year) was associated with anxiety/depression withdrawal symptoms but not weakness symptoms, while family history of drug problems was associated with weakness but not anxiety/depression withdrawal symptoms. Major depressive disorder and personality disorders were associated with both types of withdrawal symptoms, generalized anxiety disorder was not associated with either type, and panic disorder was associated with only the anxiety/depression withdrawal symptoms.
