The U.K. replication sample (RADIANT) included 1636 patients with a diagnosis of recurrent major depression (except for 20 with first episode) recruited within the Depression Case Control (DeCC) study, the Depression Network (DeNET) affected siblings linkage study and the Genome-Based Therapeutics in Depression (GENDEP) study (Lewis et al., 2010b). The matched screened controls described in Lewis et al,. 2010 (N = 1594) and the publicly available controls from the Wellcome Trust Case Control Consortium 2 (N = 5652) were used for this analysis.
