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Chunk #42 — EXPERIMENTAL PROCEDURES — MARS (GWAS) sample

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The neuronal transporter gene SLC6A15 confers risk to major depression.
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The Rotterdam study subsample included 7983 from the Rotterdam Study, a prospective cohort study from 1990 conducted in the Netherlands. All inhabitants aged 55 and over were eligible (Hofman et al., 2007). Depression was ascertained using the CES-D, a semi-structured interview with the Present State Examination (PSE) by a clinician as well as GP-records and specialist letters.