To compute the correlations between global network characteristics and clinical symptoms for BD patients, the same threshold was applied to compute network measures for SL matrix with 30% of connection density. Correlation coefficients between MADRS scores and λ and σ were significant in the gamma band network of BD patients (λ: r = 0.353, p = 0.008, σ: r = − 0.292, p = 0.030) (Fig. 7). However, correlations between MADRS scores and other network measures (C, L, γ, and Eg) were not significant. No significant correlations were found between YMRS and network measures.
