revealed that our selected genes are involved in neuron-related activity (Table 8). Overall, pathway and mouse phenotype enrichment analyses confirmed the results obtained from the GO term enrichment analysis by WebGestalt, and these analyses also revealed highlighted genes related to synaptic activity and GABA signaling as being particularly represented in significant pathways and mouse phenotypes. Finally, we queried PubMed references by ToppFun to search for publications that are overrepresented with genes from our top ranked list (Table 9). The highest scored record from this analysis was from a genetic study of gene expression associated with alcohol consumption in rats and humans [4], in which 24 of our top genes were represented in the total of 130 genes described by this study and showed significant enrichment (p < 1 × 10-6). The second highest scored record was from an association study of 182 candidate genes in anorexia nervosa (enrichment p < 1 × 10-6).
