Results of haplotype analyses within confidence interval defined blocks are shown in Table 2. Compared to single marker analyses, we observe an increased association in block 3 (containing rs1344706) on a haplotype (frequency 0.188 in controls) bearing the common alleles of rs7605689 (T) and rs3931790 (T), the rare allele of rs7603001 (A) and the previously associated common (A) allele of rs1344706 (Χ2= 8.626, p<0.003). The increased significance is due to a larger case/control difference (5%) in the frequency of this TTAA haplotype compared to the difference for the A allele of rs1344706 (4%).
