At all healthcare visits, smokers such as the woman described in the vignette should be encouraged to quit and queried about their willingness to make a quit attempt. Because she was initially unwilling to try to quit, either Motivational Interviewing (Table 1) or the “5 Rs” should be used at each visit. There is more evidence supporting the use of the former, but it is more time consuming and requires greater training. In addition, patients who are willing to try to reduce their smoking should be encouraged to use the Smoking Reduction+NRT treatment (Table 1) with the understanding that this treatment should be used for at least several months.