Another area of focus the Substance Use Workgroup identified is detailed measurement of substance use patterns, including detailed quantity, frequency, route of administration, and co-use patterns. This information is critical in order to complete one of the aims of the ABCD Study: to characterize the impact of substance exposure on adolescent neurocognitive development. Adolescents demonstrate a greater impact of substance use on neurocognitive outcomes (Volkow et al., 2014). Alcohol has historically been the most commonly used substance in adolescents (Johnston et al., 2017) and converging lines of evidence reflect that repeated alcohol use during adolescence, especially binge drinking, has been associated with poor neurocognitive outcomes such as brain structural and function abnormalities and reduced memory, visuospatial skills, attention, and executive function in adolescents (Lisdahl et al., 2013; Jacobus et al., 2015; Nguyen-Louie et al., 2016; Pfefferbaum et al., 2016; Brumback et al., 2016; Meruelo et al., 2017; Squeglia et al., 2015; Müller-Oehring et al., 2017; Sullivan et al., 2016; Whelan et al., 2014). Alcohol hangover symptoms not only reflect an immediate consequence of excessive consumption that causes distress in the
