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Chunk #10 — Results — The metaGRS improves risk prediction of ischaemic stroke compared with other genetic scores

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Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke.
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There was no evidence for a statistical interaction of the metaGRS with sex on IS hazard (Wald test in Cox proportional hazard model, P = 0.614), indicating that the substantial differences in cumulative incidence between the sexes were driven by differences in baseline hazards rather than by any sex-specific effects of the metaGRS itself.