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Chunk #12 — METHODS — Parent-of-origin specific associations

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Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.
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score reflecting the relative likelihood of the two possible parental origin assignments. Haplotypes from consecutive tiles were then stitched together based on sharing at the overlapping region. For haplotypes derived by stitching, a contig-score for parental origin was computed by summing the individual single-tile scores. Similarly, parent-of-origin specific allelic associations at imprinted loci were also sought in the deCODE blood cells and adipose tissue expression datasets.