The secondary hypotheses related to the prediction of interactions among the more robust predictors of developing an AUD. Indeed, the FH of AUDs and baseline drinking did interact such that the impact of FH was only observed for subjects with higher T1 drinking levels. This may indicate that efforts to help children of alcoholics to keep their drinking quantities low in the late teens and early adulthood may help decrease the AUD risk associated with their FH. While it is also possible that additional characteristics such as lower socioeconomic status (SES) and higher levels of antisocial behavior might have been more prevalent in those with higher early drinking, these mechanisms may be less likely to operate in the higher educated, higher income, more functional SDPS probands studied here.
