The VIVA LA FAMILIA Study is unique in its consideration of a pediatric Hispanic population. We believe that our extensive phenotyping and genotyping enabled localization of novel genetic loci associated with obesity in Hispanic children, despite our relatively small sample size. Our phenotypes represent not only adiposity, but also biological processes underlying the development and consequences of childhood obesity. We applied a standard and stringent approach to our measured genotype analysis, but do agree replication is desirable. We believe we have identified genes that warrant further investigation.
