Evidence suggests that the reduced amplitude of P3 in high-risk subjects may serve as a marker of susceptibility to alcoholism. One required characteristic of a marker is heritability; analysis of data from COGA suggests that P3 amplitude may be genetically influenced. Researchers are continuing to study COA’s from densely affected families who participated in COGA to confirm whether COA’s who exhibit low P3 amplitudes are most at risk for developing alcoholism.
